Date rape fantasy

Added: Tung Littlefield - Date: 26.07.2021 13:58 - Views: 26116 - Clicks: 3120

Researchers are closer to understanding the biology behind GHB, a transmitter substance in the brain, best known in its synthetic form as the illegal drug fantasy. In the s, gamma-hydroxybutyric acid GHB was first discovered as a naturally occurring substance in the brain. Since then it has been manufactured as a drug with a clinical application and has also developed a reputation as the illegal drug fantasy and as a date rape drug. Its physiological function is still unknown. Now a team of researchers at the Department of Drug De and Pharmacology at the University of Copenhagen has shown for the first time exactly where the transmitter substance binds in the brain under physiologically relevant conditions.

The have recently been published in the Proceedings of the National Academy of Sciences. The binding is strong even at very low dosage. This suggests that we have found the natural receptor, which opens new and exciting research opportunities, in that we have identified an important unknown that can provide the basis for a full explanation of the biological ificance of the transmitter," says Laura Friis Eghorn, PhD student.

Fantasy is also used as a so-called date rape drug, because in moderate amounts it has sedative, sexually stimulating and soporific effects. Date rape fantasy compound is also abused for its euphoric effect, but in combination with alcohol, for example, it is a deadly cocktail that can lead to a state of deep unconsciousness or coma. In the long-term, understanding how GHB works will enable us to develop new and better pharmaceuticals with a targeted effect in the brain, without the dangerous side-effects of fantasy," explains Laura Friis Eghorn, Department of Drug De and Pharmacology.

Fantasy is an extremely toxic euphoriant, because the difference between a normal intoxicating dose and a fatal dose is so small. A better understanding of the biological mechanisms behind Date rape fantasy in the brain will benefit research into a life-saving antidote for this drug. Today there is no known antidote. Statistics from Denmark in show that percent of young people who frequent night clubs have had experience with Fantasy.

However, since the drug is often also used in private for its sedative effect, it is difficult to estimate the extent of abuse. The new research findings are the result of a collaboration between researchers at the University of Sydney in Australia and medicinal chemists at the Faculty of Health and Medical Sciences:. This enabled us to go on a targeted fishing expedition in the brain.

We have slowly found our way to the receptor, which we have also been able to test pharmacologically. In itself, it is not unusual to find new receptors in the brain for known compounds. However, when we find a natural match rooted in the brain's transmitter system, the biological implications are extremely interesting," explains Petrine Wellendorph, associate professor and head of the responsible research group that produced the pioneering. Materials provided by University of Copenhagen.

Note: Content may be edited for style and length. Science News. Illegal use and possible antidote Fantasy is also used as a so-called date rape drug, because date rape fantasy moderate amounts it has sedative, sexually stimulating and soporific effects.

Researchers on a targeted fishing expedition The new research findings are the result of a collaboration between researchers at the University of Sydney in Australia and medicinal chemists at the Faculty of Health and Medical Sciences: "Our chemist colleagues deed and produced special ligands -- that are mimics of GHB in several variations. Story Source: Materials provided by University of Copenhagen. Eghorn, Inge S. Olsen, Gitte M. Clausen, Mary Chebib, and Petrine Wellendorph.

Proceedings of the National Academy of Sciences. ScienceDaily, 2 July University of Copenhagen. New brain receptor for drug 'fantasy' identified. Retrieved July 15, from www. The process has the potential to impact nanomanufacturing The vaccine blunts the illegal stimulant's effects on the brain, which could help ScienceDaily shares links with sites in the TrendMD network and earns revenue from third-party advertisers, where indicated. Print Share. Tastes Great? Boy or Girl? Living Well. View all the latest top news in the environmental sciences, or browse the topics below:.

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Date rape fantasy

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